CANOC - UK CHIC Collaboration
- Types of
- CANOC UK – CHIC
Collaboration Management Team
In September 2013, data from the CANOC collaboration was merged with data from the United Kingdom Collaborative HIV Cohort (UK CHIC) Study, providing a unique collaborative research opportunity.
The UK CHIC study is a collaborative cohort of 19 participating HIV centres in England and Scotland, established in 2001 to conduct surveillance and evaluate treatment uptake and clinical outcomes of HIV-positive individuals accessing care in the UK. The UK CHIC study includes over 45,000 participants aged over 16 years, who have received HIV care at one of the collaborating centres from 1996 onwards.
The CANOC – UK CHIC Collaboration seeks to evaluate the differences in demographic profiles, healthcare provision and clinical outcomes for individuals living with HIV and accessing care in Canada and the UK.
Data collected as part of this Collaboration include:
- Demographic information (sex, age, HIV risk factors, ethnicity, country of birth)
- Clinical information (date of death, year of entry into care, hepatitis C co-infection, AIDS-defining illnesses: type, date of diagnosis)
- Laboratory tests (CD4 count, date of CD4 count, viral load measurement, assay type, date of viral load measurement, ART resistance testing)
- Antiretroviral drug use (type, start date, stop date)
Robert Hogg (CANOC PI), Caroline Sabin (UK CHIC PI), Hasina Samji (Collaboration Coordinator), Sophie Jose (UK CHIC Biostatistician), Sophie Patterson (CANOC Research Assistant)
S Jose, K Chan, H Samji et al. A comparison of virologic outcomes among HIV-positive individuals receiving HAART in Canada and the UK. Poster presentation, presented by S Jose at the British HIV Association Conference, Liverpool, England. 1-4 April 2014.
S Patterson, H Samji, K Chan et al. CANOC- UK CHIC Collaboration. Mortality among ART recipients; a comparison between patients in the United Kingdom and Canada. Poster presentation, presented by H Samji at the 23rd annual conference of The Canadian Association for HIV Research (CAHR), St John’s, Newfoundland, May 1-4 2014
Journal: HIV Medicine, 2017
For more information about the UK CHIC Study, please see the UK CHIC website: http://www.ukchic.org.uk
The Canadian HIV Women’s Sexual and Reproductive Health Cohort Study, or CHIWOS, is a multi-site, interdisciplinary, community-collaborative cohort study, enrolling over 1,400 women liven with HIV in British Columbia, Ontario and Quebec. The overall study aims to understand whether and how women-centered HIV care may improve health outcomes for women living with HIV in Canada. CHIWOS is committed to the principles of GIPA (Greater Involvement of People Living with HIV/AIDS) and MIWA (Meaningful Involvement of Women Living with HIV/AIDS), and involves HIV-positive women in all stages of the research process, from conceptualization and study design, to survey development, to implementation and analysis.
CHIWOS and CANOC plan to link the robust CANOC clinical data with key socio-behavioural variables collected by CHIWOS to facilitate detailed study into the health of women living with HIV in Canada.
For more information on CHIWOS, please visit: http://www.chiwos.ca
- Assess the proportion, distribution and patterns of use and uptake of women-specific HIV/AIDS services, and factors associated with service uptake among HIV-positive women living in Canada.
- Estimate the effect of women-specific HIV/AIDS services uptake on the sexual and reproductive and mental health outcomes and women’s health outcomes and screening of women living with HIV in Canada.
Data collected by this multi-site cohort study include:
- Demographic information (age, gender, sexual orientation, ethnicity, country of birth)
- Socio-economic information (education, income)
- Clinical information (co-morbidities, CD4 count, viral load, ARV use)
- Health care and support service access/use
- Sexual and reproductive health
- Experiences with stigma, discrimination, violence, and abuse
The Comparison of Outcomes and Service Utilization Trends (COAST) study is an initiative of the Epidemiology and Population Health program at the BC-CfE. It is a population-based retrospective study comprising three defined cohorts including de-identified health-related data from the BC-CfE and Population Data BC. The three defined COAST cohorts are: HIV-positive individuals ever on anti-retroviral therapy (ART), HIV-positive individuals never on ART, and a random sample of adults drawn from the general BC population. The data obtained is from the period April 1, 1996 – March 31 2013.
There is limited understanding regarding the impact of long-term ART use on aging, future patterns of morbidity and mortality, and how this will affect health resources among HIV-positive individuals. A unique aspect of the COAST study is the comparison over time of health outcomes and resource utilization between HIV-positive individuals and the general population.
The COAST study aims to:
- Evaluate determinants of health outcomes and health care services utilization among HIV-positive adults in the ART era in British Columbia, Canada.
- Assess how these may differ from those observed in a random sample of the general population of BC.
Individuals interested in pursuing analyses with COAST should contact the study coordinator Oghenowede Eyawo at firstname.lastname@example.org for more information.
Journal: BMC Infect Dis, 2017
Journal: AIDS and Behavior, 2017
Journal: Lancet HIV, 2017
Journal: AIDS, 2016